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Matrix-assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry

In general, MALDI-TOF/MS  can be rapidly analyzed the samples' molecular weight such organic compounds, inorganic compounds, polymers, surfactants, dyes, macromolecules, dendrites and various biochemical molecules (e.g. peptides, lipids, carbohydrates, nucleotides, and proteins, etc.). Tandem mass spectrometry (MS/MS) also can be performed to obtain further target's production ions to assist on unknown sample characterization.

Equipment Description

  • Model:Shimadzu, MALDI-7090 TOF/TOF
  • Specification:
  1.  Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
  2.  High-vacuum, high-speed solid-state laser matrix-assisted laser desorption/ionization source
  3.  Multi-sample plate introduction system
  4.  Time-of-flight tandem mass spectrometer
  5.  Coherent spatially-resolved focusing technology provides high-resolution and accurate MS/MS
  6.  High-energy and low-energy fragmentation techniques

Service Items

  • MALDI-TOF/MS
  • MALDI-Imaging
  • LC/MS/MS
  • GC/MS

Charges

  1.  MALDI primary mass spectrometry qualitative analysis: NT$300/piece (non-project NT$1,500/piece)
  2.  MALDI secondary mass spectrometry analysis (including primary mass spectrometry qualitative analysis): NT$350/piece (non-project NT$1,800/piece)
  3.  MALDI-IMS primary mass spectrometry qualitative analysis: NT$10,000/piece (non-project NT$50,000/piece)
  4.  ESI low-resolution primary mass spectrometry qualitative analysis: NT$300/piece (non-project NT$1,500/piece)
  5.  ESI low-resolution secondary mass spectrometry analysis (including primary mass spectrometry qualitative analysis): NT$350/piece (non-project NT$1,800/piece)
  6.  LCMS primary mass spectrometry qualitative analysis: NT$1,200  /piece (non-project NT$3,000/piece)
  7.  LCMS secondary mass spectrometry analysis: NT$50/peak (non-project NT$100/piece)
  8.  LCMS chromatographic conditions optimization (including mobile phase replacement and gradient setting): NT$3,000/piece (non-project NT$6,000/piece)
  9.  LCMS quantitative analysis:
    • One set of calibration curve for the initial analysis: NT$8,000/piece (non-project NT$10,000/piece), including establishment, optimization, and confirmation of linear conditions
    • One set of test calibration curve for subsequent tests: NT$3,000/piece (non-project NT$6,000/piece)
    • For samples with fewer than 10 target analytes, the cost is NT$1,200/piece (non-project NT$2,000/piece)
    • For samples with more than 10 target analytes, an additional NT$250/piece (non-project NT$500/piece) will be charged for every additional 5 target analytes
  10.  GC/MS primary mass spectrometry qualitative analysis:NT$1,000/piece (non-project NT$2,000/piece)
  11.  GC/MS database search:NT$50/peak (non-project NT$100/piece)
  12.  Urgent samples:Double the original price of the service (the analysis will be completed within 1-3 days after receiving the sample, while regular samples will be completed within 7-14 days after receiving the sample)

Sample Preparation

  • For solid samples, please note the type of solvent.
  • For protein identification, please complete the sample separation and digestion before delivering the sample.
  • For MALDI-IMS analysis, please contact with the technical staff first to discuss the requirements for sample delivery.
  • No accepting radioactive and biosafety samples; please note toxic samples.

Contact Detail

Instrument expert: Prof. Jentaie Shiea
Technical staff: Min-Zong Huang
contact method: (07)5252000 ext. 5832 nsysuchemshiea@gmail.com
Place: International building B1 IR0001 Lab
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